Medicine

Advancing ASO therapies from advancement to application

.Completing enthusiasms.R.S., M.S., H.G. and also A.A.R. are actually organizers of the 1M1M campaign. H.G. and A.A.R. are actually panel of directors participants and R.S., M.S. and also A.A.R. are members of the scientific consultatory board of N1C. A.A.R. discloses work through LUMC, which has licenses on exon-skipping technology, some of which has actually been certified to BioMarin and also subsequently sublicensed to Sarepta. As co-inventor of some of these licenses, A.A.R. was entitled to a reveal of nobilities. A.A.R. additionally makes known working as impromptu professional for PTC Therapies, Sarepta Therapeutics, Regenxbio, Dyne Rehabs, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco as well as Astra Zeneca. Over the last 5 years, A.A.R. additionally did ad hoc speaking with for Alpha Anomeric. A.A.R. also states registration of the clinical advisory boards of Eisai, Hybridize Rehabs, Muteness Rehabs, Sarepta Rehabs, Sapreme as well as Mitorx. Previously 5 years, A.A.R. was actually additionally a scientific board of advisers participant for ProQR. Reimbursement for A.A.R. u00e2 s consulting and advising activities is paid out to LUMC. Before 5 years, LUMC likewise obtained sound speaker gratuity coming from PTC Rehabs, Alnylam Netherlands, Italfarmaco and Pfizer and also moneying for arrangement research study coming from Sapreme, Eisai, Galapagos, Synaffix as well as Alpha Anomeric. Task financing is actually acquired from Sarepta Therapies and Entrada using unregulated gives. H.G. possesses nothing at all to reveal in regard to the topics covered in this document. Before 5 years, he has actually likewise gotten working as a consultant honoraria coming from UCB. M.S. acquired working as a consultant honoraria from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly as well as Solaxa previously 5 years, all unassociated to today composition. R.S. possesses absolutely nothing to disclose relative to the subjects covered in this composition. She has gotten speaker and/or working as a consultant honoraria or even funding contributions from Abbvie, Bial, STADA and also Everpharma before 5 years.

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